发明名称 Suspension of an Epi-Hne Protein, process of preparation thereof, dry powder aerosol derived therefrom, pharmaceutical compositions containing said suspension or aerosol, and their uses.
摘要 A suspension of an EPI-hNE protein, said suspension being characterised in that the EPI-hNE protein is present in the form of crystalline particles mostly having a diameter comprised between 1 and 6 mu m, in particular between 3 and 6 mu m, as determined by laser granulometry, the concentration of the suspension in EPI-hNE-4 being comprised between 1 and 15 mg/ml, preferably between 2 and 10 mg/ml, in an aqueous vehicle at a pH comprised between 3 and 8, preferably 4 and 6, most preferably at a pH of 4.0 to 5.0.
申请公布号 ZA200302876(B) 申请公布日期 2004.04.28
申请号 ZA20030002876 申请日期 2003.04.11
申请人 DEBIOPHARM S.A. 发明人 ALAIN PONCIN;FRANCOIS SAUDUBRAY;ANNE BOKMAN
分类号 A61K9/00;A61K38/57 主分类号 A61K9/00
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