发明名称 |
Papillomavirus polyprotein constructs |
摘要 |
A papillomavirus polyprotein construct comprises at least two amino acid sequences fused directly or indirectly together, each of the sequences being the sequence of an early ORF protein of papillomavirus or an immunogenic variant or fragment thereof, and at least one of said sequences being other than the E6 or E7 protein sequence or an immunogenic variant or fragment thereof. Nucleic acid molecules encoding the polyprotein construct, prophylactic or therapeutic compositions comprising the polyprotein construct or the nucleic acid molecule, and methods for eliciting an immune response against papillomavirus in a host animal are also provided.
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申请公布号 |
US6726912(B1) |
申请公布日期 |
2004.04.27 |
申请号 |
US20010011749 |
申请日期 |
2001.12.11 |
申请人 |
CSL LIMITED;UNIVERSITY OF QUEENSLAND OF ST. LUCIA |
发明人 |
WEBB ELIZABETH ANN;MARGETTS MARY BRIGID;COX JOHN COOPER;FRAZER IAN;MCMILLAN NIGEL ALAN JOHN;WILLIAMS MARK PHILIP;MOLONEY MARGARET BRIDGET HOLLAND;EDWARDS STIRLING JOHN |
分类号 |
C12N15/09;A61K31/00;A61K39/00;A61K39/12;A61P31/00;A61P31/12;C07K14/025;C12N1/21;C12N15/00;C12P21/02;C12R1/19;C12R1/92;(IPC1-7):A61K39/12;C12P19/34 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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