| 摘要 |
A compound of the formula (I):wherein: R<1 >is represented by the formula:wherein R<4>, R<5>, R<6>, R<7 >and R<8 >are monovalent radicals such as: hydrogen, halogen, optionally substituted lower alkyl, lower alkyloxy, lower alkylthio, optionally substituted amino, nitro; non-aromatic heterocyclic group, and the like with certain provisos;Y is -OH or -NHOH;R<2 >is hydrogen, optionally substituted lower alkyl, or optionally substituted aralkyl;R<3 >is halogen, hydroxy, lower alkyloxy, or lower alkylthio;(b) n is an integer from 1 to 3;its optically active substance, its prodrug, its pharmaceutically acceptable salt, and its solvate.
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