发明名称 |
PYRAZOLONE COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATOR |
摘要 |
<p>A preventive, therapeutic or improving agent for diseases against which activation of the thrombopoietin receptor is effective or a platelet increasing agent, which contains a thrombopoietin receptor activator represented by the formula (1): wherein A is a C<2-14#191 aryl group, B is a hydrogen atom, a C?1-6#191 alkyl group, a C?1-3#191 alkyl group substituted with one or more fluorine atoms or a C?2-14#191 aryl group, D is a hydrogen atom, a C?1-6#191 alkyl group, a C?1-3#191 alkyl group substituted with one or more fluorine atoms or a C?2-14#191 aryl group, and E is a C?2-14#191 aryl group, a tautomer, prodrug or pharmaceutically acceptable salt of the activator or a solvate thereof, as an active ingredient.</p> |
申请公布号 |
WO2004033433(A1) |
申请公布日期 |
2004.04.22 |
申请号 |
WO2003JP12985 |
申请日期 |
2003.10.09 |
申请人 |
NISSAN CHEMICAL INDUSTRIES, LTD.;MIYAJI, KATSUAKI;ISHIWATA, NORIHISA;NAKAMURA, TAKANORI |
发明人 |
MIYAJI, KATSUAKI;ISHIWATA, NORIHISA;NAKAMURA, TAKANORI |
分类号 |
A61P1/16;A61P35/00;C07D231/26;(IPC1-7):C07D231/22;C07D409/12;C07D403/04;C07D401/04;A61K31/415;C07D403/12 |
主分类号 |
A61P1/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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