摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide an animal capable of being utilized as a model for a pathlogic condition of disease, such as obesity, and capable of being used in clarifying a mechanism of the pathologic condition, examining a therapeutic means for the disease, and screening prophylactics/remedies for the disease. <P>SOLUTION: This gene-introduced non-human mammal has a DNA into which an alien human SLT gene or a variant gene thereof is integrated. Further, the non-human mammal is hybridized with another model animal for the pathologic condition of the disease of obesity, hyperphagia, insulin resistance, affective psychosis, dysmnesia or hypogonadism, so that the other non-human mammal is obtained. <P>COPYRIGHT: (C)2004,JPO</p> |