| 摘要 |
<p>The present invention discloses a method for determining metabolism of a metabolite, comprising the steps: a) adding a biological sample adjacent to or upon a matrix, said matrix comprising immobilized blood cells or a blood substitute; b) incubating said matrix in the presence of said metabolite; c) assessing the degree of hemolysis occurring in said matrix, wherein a large degree of hemolysis is equated with a high degree of metabolism of said metabolite. In a preferred embodiment, alcohol is the metabolite utilized. The invention further discloses a kit for measuring the ability of a sample, to metabolize alcohol. Also disclosed is a method for determining whether a subject has a high risk of developing cancer. Further disclosed are a method for evaluating the cytotoxicity of an entity, and a method for evaluating the ability of matter to prevent cytotoxicity.</p> |
