| 发明名称 |
USE OF CALMODULIN KINASE II INHIBITORS TO TREAT MYOCARDIAL DYSFUNCTION IN STRUCTURAL HEART DISEASE |
| 摘要 |
The present invention provides a method for treating structural heart disease in a subject, comprising administering an effective amount of an inhibitor of CaMKII to the subject, whereby the administration of the inhibitor treats the structural heart disease in the subject. Also provided are transgenic animal models for treating structural heart disease. Further provided is a means of screening for a compound that can treat structural heart disease.
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| 申请公布号 |
WO03029428(A8) |
申请公布日期 |
2004.04.22 |
| 申请号 |
WO2002US31496 |
申请日期 |
2002.10.01 |
| 申请人 |
VANDERBILT UNIVERSITY;ANDERSON, MARK |
发明人 |
ANDERSON, MARK |
| 分类号 |
A01K67/027;A61K31/18;A61K38/00;A61K38/10;A61K38/16;A61K38/55;A61K45/00;A61P9/04;A61P9/10;A61P43/00;C07K7/08;C07K14/00;C12Q1/48;G01N33/15;G01N33/50;G01N33/68;(IPC1-7):A61K38/00;A61K38/51;A61K38/52;C12N9/12 |
主分类号 |
A01K67/027 |
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