发明名称 Heteroaryl alkyl piperazine derivatives as fatty acid oxidation inhibitors.
摘要 Novel compounds of the general formula:and pharmaceutically acceptable acid addition salts thereof, wherein the compounds are useful in therapy to protect skeletal muscles against damage resulting from trauma or to protect skeletal muscles subsequent to muscle or systemic diseases such as intermittent claudication, to treat shock conditions, to preserve donor tissue and organs used in transplants, in the treatment of diabetes, in the treatment of cardiovascular diseases including atrial and ventricular arrhythmias, Prinzmetal's (variant) angina, stable angina, and exercise induced angina, congestive heart disease, and myocardial infarction.
申请公布号 ZA200302990(B) 申请公布日期 2004.04.22
申请号 ZA20030002990 申请日期 2003.04.16
申请人 THERAPEUTICS, INC. 发明人 ZABLOCKI, JEFF, A.;IBRAHIM, PRABHA, N.;KEVIN SHENK;ELFATIH ELZEIN;VENKATA PALLE
分类号 A61K9/08;A61K9/20;A61K9/48;A61K31/496;A61K31/498;A61P7/00;A61P9/06;A61P9/10;A61P21/00;A61P39/00;A61P43/00;C07D209/42;C07D213/65;C07D215/20;C07D215/22;C07D215/233;C07D215/38;C07D217/02;C07D241/44;C07D263/56;C07D263/57;C07D263/58;C07D277/62;C07D277/64;C07D277/66;C07D277/68;C07D277/82;C07D295/15;C07D417/12;C07D419/12;C07D487/08 主分类号 A61K9/08
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