CELL GROWTH REGULATOR

摘要

Using L-2-phenylglycine which is seemingly an amino acid transporter ATB<0,+> inhibitor as a test substance, a human colon cancer cell line and a human mammary cancer cell line are subjected to a cell growth test. As a result, a concentration-dependent effect of regulating cell growth is found out. This fact indicates that cell growth can be regulated by inhibiting the activity of ATB<0,+>. It is expected that the regulation of the amino acid transporter ATB<0,+> activity is usable as an important indicator in developing a growth regulator for cancer cells and the like.