NOR-1 AND NUR77 NUCLEAR RECEPTORS AS TARGETS FOR ANTI-LEUKEMIA THERAPY
摘要
The present invention is directed to the application of nuclear receptor transcription factors as molecular targets for therapeutic intervention in the treatment of myeloid leukemia. More specifically, nor-1 and nur77 nuclear receptors are targets for myeloid leukemia therapy. The figure shows the growth curve of one litter including two nor-1KO/nur77KO mice and their normal littermates that is representative of a number of litters that were weighed daily for a period of two weeks.
申请公布号
WO03088812(A3)
申请公布日期
2004.04.22
申请号
WO2003US11804
申请日期
2003.04.15
申请人
BAYLOR COLLEGE OF MEDECINE;WASHINGTON UNIVERSITY;MULLICAN, SHANNON, E.;CONNEELY, ORLA, M.;MILBRANDT, JEFFREY