发明名称 |
Inhalabel formulation of a solution containing a tiotropium salt. |
摘要 |
A medicament preparation (A) contains: (a) a tiotropium salt as active agent (I), at a tiotropium concentration of 0.0005-5 wt.%; (b) water or aqueous ethanol as solvent; (c) acid to adjust the pH to 2.0-4.5; (d) a preservative; and (e) optionally (f) one or more of complexants, stabilizers, co-solvents and other auxiliaries. An independent claim is included for the production of (A), by mixing the individual components. ACTIVITY : Bronchodilator; Antiasthmatic. No biological test data provided. MECHANISM OF ACTION : Anticholinergic. No biological test data provided. |
申请公布号 |
ZA200302922(B) |
申请公布日期 |
2004.04.22 |
申请号 |
ZA20030002922 |
申请日期 |
2003.04.14 |
申请人 |
BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG. |
发明人 |
BARBARA NIKLAUS-HUMKE;CHRISTEL SCHMELZER;PETRA BARTH;KARIN DRECHSEL |
分类号 |
A61K9/72;A61K9/00;A61K31/439;A61K31/46;A61K31/4745;A61K31/5365;A61K31/537;A61K31/5386;A61K47/10;A61K47/16;A61K47/18;A61P11/06 |
主分类号 |
A61K9/72 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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