发明名称 DIHYDRONAPHTHALENE DERIVATIVE COMPOUND AND PHARMACEUTICAL AGENT CONTAINING THE COMPOUND AS EFFECTIVE INGREDIENT
摘要 PROBLEM TO BE SOLVED: To obtain a compound having activity to control a peroxisome proliferator-activated receptor, and a pharmaceutical agent containing the compound as an effective ingredient. SOLUTION: The controlling agent of peroxome proliferator-activated receptor contains a compound expressed by formula (I), its salt and its compound as effective ingredients. The agent is useful as a blood sugar depressant, a hypolipidemic agent, an agent for preventing and/or treating diabetes, metabolically abnormal diseases such as obesity, syndrome X, hypercholesterolemia, hyperlipoprotemia, and hyperlipidemia, athlerosclerosis, hypertension, disorder of cardiovascular system, hyperphagia, ischemic heart diseases, and the like, also as an HDL cholesterol elevation agent, a reducing agent of LDL cholesterol and/or VLDL cholesterol and a risk factor-reducing agent of diabetes, syndrome X, and the like. COPYRIGHT: (C)2004,JPO
申请公布号 JP2004123721(A) 申请公布日期 2004.04.22
申请号 JP20030283699 申请日期 2003.07.31
申请人 ONO PHARMACEUT CO LTD 发明人 TAJIMA HISAO;NAKAYAMA KOSUKE;FUKUSHIMA DAIKICHI
分类号 C07D277/20;A61K31/4164;A61K31/422;A61K31/4439;A61K31/454;A61K31/4545;A61K31/496;A61K31/497;A61K31/5377;A61K31/541;A61P3/04;A61P3/06;A61P3/10;A61P9/00;A61P9/10;A61P9/12;A61P43/00;C07D263/32;C07D277/42;C07D413/04;C07D413/12;C07D417/04;(IPC1-7):C07D277/20;A61K31/416;A61K31/443;A61K31/537 主分类号 C07D277/20
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