| 发明名称 |
PYRAZOLE COMPOUNDS FOR TREATMENT OF NEURODEGENERATIVE DISORDERS |
| 摘要 |
The invention provides compounds of Formula (I): wherein R1,R2,R3, R4,R6,R7, R8 and A are as defined. Compounds of formula (I) have activity inhibiting production of A.beta.-peptide. The invention also provides pharmaceutical compositions and methods for treating diseases, for example Alzheimer's disease, in mammals comprising compounds of Formula (I).
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| 申请公布号 |
CA2501799(A1) |
申请公布日期 |
2004.04.22 |
| 申请号 |
CA20032501799 |
申请日期 |
2003.09.26 |
| 申请人 |
PFIZER PRODUCTS INC. |
发明人 |
ALLEN, MARTIN PATRICK;CHEN, YUHPYNG L.;LIRAS, SPIROS;ROSATI, ROBERT L. |
| 分类号 |
A61P25/00;C07D231/40;C07D401/06;C07D401/12;C07D403/04;C07D403/06;C07D405/04;C07D409/04;C07D409/12;C07D413/14;C07D471/04;C07D487/04;(IPC1-7):C07D231/40;C07D221/00;C07D231/00;C07D249/00;C07D253/00;A61K31/415 |
主分类号 |
A61P25/00 |
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