Histone deacetylase inhibitors for the treatment of multiple sclerosis, amyotrophic lateral sclerosis and Alzheimer's Disease

摘要

The present invention provide therapies for Alzheimer's Disease (AD), multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS). The method relies on the use of an HDAC inhibitor, alone or in combination with other drugs, to prevent or treat AD, MS or ALS. Also provided are methods of screening for additional HDAC inhibitors with particular efficacy against these disease states.