| 发明名称 |
Propanoic acid derivatives that inhibit the binding of integrins to their receptors |
| 摘要 |
A compound of the structureA method for the inhibition of the binding of alpha4beta1 integrin to its receptors, for example VCAM-1(vascular cell adhesion molecule-1) and fibronectin; pharmaceutically active compositions comprising these compounds; and the use of these compounds for the control or prevention of diseases states in which alpha4beta1 is involved are also disclosed.
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| 申请公布号 |
US6723711(B2) |
申请公布日期 |
2004.04.20 |
| 申请号 |
US20010973414 |
申请日期 |
2001.10.09 |
| 申请人 |
TEXAS BIOTECHNOLOGY CORPORATION |
发明人 |
BIEDIGER RONALD J.;DUPRE BRIAN;HAMAKER LINDA K.;HOLLAND GEORGE W.;KASSIR JAMAL M.;LI WEN;MARKET ROBERT V.;NGUYEN NOEL;SCOTT IAN L.;WU CHENGDE;DECKER E. RADFORD |
| 分类号 |
A61P29/00;A61P35/00;C07C;C07D213/64;C07D317/60;C07D405/12;C07D409/14;(IPC1-7):C07D213/64;C07D239/36;A61K31/441;A61K31/513;A61D11/06 |
主分类号 |
A61P29/00 |
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