发明名称 USE OF THIAZOLE DERIVATIVES FOR PREPARING A MEDICINE FOR PROTECTING MITOCHONDRIA.
摘要 <p>The invention concerns compounds of general formula (I), wherein: A represents one of the radicals in which R5 represents independently a hydrogen atom, or alkyl; R6, R7 and R8 independently represent a hydrogen atom, alkyl, cycloalkyl, hydroxy or alkoxy; R11 represents a hydrogen atom of alkyl; and R9, R10 and R12 independently represent a hydrogen atom, alkyl, hydroxy or alkoxy; B represents a hydrogen atom or alkyl; n represents an integer from 0 to 5; R1 and R2 independently represent a hydrogen atom, alkyl or cycloalkyl; R3 and R4 independently represent a hydrogen atom or an alkyl radical, or R3 and R4 together form with the nitrogen atom which bears them a heterocycle optionally substituted comprising in all 1 to 2 heteroatoms and 5 to 7 members. Said compounds can be used for preparing a medicine for protecting mitochondria, and in particular a medicine for preventing or treating cirrhosis.</p>
申请公布号 MXPA04000752(A) 申请公布日期 2004.04.20
申请号 MX2004PA00752 申请日期 2002.07.25
申请人 SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) 发明人 PIERRE-ETIENNE CHABRIER DE LASSAUNIERE
分类号 C07D277/28;A61K31/426;A61K31/427;A61K31/496;A61K31/5415;A61P1/00;A61P1/16;A61P9/04;A61P21/00;A61P25/00;A61P25/28;A61P27/02;A61P27/16;A61P29/00;A61P31/04;A61P35/00;A61P39/02;A61P43/00;C07D417/04;(IPC1-7):A61K31/426 主分类号 C07D277/28
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