发明名称 CRF receptor antagonists and methods relating thereto
摘要 Compounds are disclosed which have utility in the treatment of a variety of disorders, including the treatment of disorders manifesting hypersecretion of CRF in a warm-blooded animals, including stroke. The compounds of this invention have the following structures:wherein n, m, R, R1, R2, X and Ar are as defined herein, including stereoisomes and pharmaceutically acceptable salts thereof.
申请公布号 US6723721(B2) 申请公布日期 2004.04.20
申请号 US20010027789 申请日期 2001.12.20
申请人 NEUROCRINE BIOSCIENCES, INC. 发明人 HADDACH MUSTAPHA;GUO ZHIQIANG;MCCARTHY JAMES R.
分类号 A61K31/4985;A61P1/00;A61P1/14;A61P3/04;A61P9/10;A61P9/12;A61P25/00;A61P25/08;A61P25/22;A61P25/24;A61P25/30;A61P29/00;A61P37/02;A61P43/00;C07D471/16;C07D487/16;(IPC1-7):A61K31/495;A61K31/50;C07D471/12;C07D487/12 主分类号 A61K31/4985
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