发明名称 PRACTICAL SYNTHESIS OF UREA DERIVATIVES
摘要 A very mild and efficient approach for the synthesis of ureas is described. Phenyl carbamates were used as intermediates for the preparation of N,N'- substituted ureas. The carbamates were treated with an approximate stoichiometric amount of amine in dimethyl sulfoxide at ambient temperature, generating the ureas in high yield. The reaction was simple, safe, fast, inexpensive, and amenable to large scale production of the product.
申请公布号 CA2215585(C) 申请公布日期 2004.04.20
申请号 CA19972215585 申请日期 1997.09.16
申请人 BOEHRINGER INGELHEIM (CANADA) LTD. 发明人 THAVONEKHAM, BOUNKHAM
分类号 C07C273/18;C07C275/04;C07C335/04;C07C335/16;C07D207/08;C07D211/58;C07D211/60;C07D213/56;C07D277/38;C07D277/40;C07D277/46;C07D295/215;C07D401/12;C07D417/12;(IPC1-7):C07C275/04 主分类号 C07C273/18
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