| 摘要 |
The invention relates to compounds of the formula (I): wherein: ring C is 9 or 10-membered bicyclic heteroaromatic group containing at least one nitrogen atom in the ring attached to Z and optionally containing a further 1-3 heteroatoms, selected independently from O, S, and N, with the proviso that ring C is not a quinazoline, quinoline or cinnoline group; either any one of G1, G2, G3, G4 and G5 is nitrogen and the other four are -CH-; or G1, G2, G3, G4 and G5 are all -CH-; Z is -O-, NH-, -S-, CH2- or a direct substituents R<1 >may be attached at any free carbon atom of the indole, azaindole or indazole group; m is an integer from 0 to 2; R<b >represents hydrogen or another value as defined herein; R<1 >represents hydrogen, hydroxy, halogeno, C1-4alkyl, or any other value as defined herein; R<2 >represents hydrogen, hydroxy, halogeno, cyano, nitro, trifluoromethyl, C1-3alkyl, C1-3alkoxy, C1-3alkylsulphanyl, -NR<3>R<4 >(wherein R<3 >and R<4>, which may be the same or different, each represents hydrogen or C1-3alkyl), or R<5>X<1>- (wherein R<5 >and X<1 >are as defined herein) and salts thereof, processes for the preparation of such compounds, pharmaceutical compositions |
