| 发明名称 |
METHOD TO IDENTIFY AGENTS ACTIVE AGAINST HCV BY USING THE STRUCTURE COORDINATES OF HEPATITIS C VIRUS PROTEASE |
| 摘要 |
The present invention relates to compositions and crystals of a hepatitis C virus protease in complex with its viral cofactor. This invention also relates to methods of using the structure coordinates of hepatitis C virus protease in complex with a synthetic NS4A to solve the structure of similar or homologous proteins or protein complexes. |
| 申请公布号 |
HK1038573(A1) |
申请公布日期 |
2004.04.16 |
| 申请号 |
HK20010108615 |
申请日期 |
2000.02.17 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
KIM, JOSEPH L.;MORGENSTERN, KURT A.;LIN, CHAO;FOX, TED;THOMSON, JOHN A. |
| 分类号 |
C07K1/00;C07K14/18;C07K19/00;C30B7/00;G01N33/576;G06F17/30;G06F19/16 |
主分类号 |
C07K1/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
