发明名称 |
METHOD FOR RATING CANCERATION DEGREE OF MAMMAL-DERIVED SPECIMEN |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for rating the canceration degree of a mammal-derived specimen based on detecting gene abnormality, suitable for evaluating diagnostic or therapeutic methods for discovering cancer at early stages. <P>SOLUTION: This method for rating the canceration degree of the mammal-derived specimen comprises (1) the 1st step of assaying the methylation frequency of PPARG angiopoietin-related protein gene contained in the specimen or an index value correlated with the methylation frequency and (2) the 2nd step of determining the canceration degree based on a difference obtained by comparing the above methylation frequency or index value with the corresponding control. <P>COPYRIGHT: (C)2004,JPO |
申请公布号 |
JP2004113115(A) |
申请公布日期 |
2004.04.15 |
申请号 |
JP20020280686 |
申请日期 |
2002.09.26 |
申请人 |
NATIONAL CANCER CENTER-JAPAN;SUMITOMO CHEM CO LTD |
发明人 |
USHIJIMA TOSHIKAZU;KANEDA ATSUSHI |
分类号 |
C12N15/09;A61K38/00;A61K45/00;A61K48/00;A61P35/00;C12Q1/02;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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