发明名称 Phosphorus-containing compounds and uses thereof
摘要 This invention concerns a new family of phosphorus-containing compounds containing a moiety JQA- in which: A is absent or is -O-, -S- or -NR<2>-; Q is absent or (if A is -O-, -S- or -NR<2>-) Q may be -V-, -OV-, -SV-, or -NR<2>V-, where V is an aliphatic, heteroaliphatic, aryl, or heteroaryl moiety, such that J is linked to the cyclohexyl ring directly, through A or through VA, OVA, SVA or NR<2>VA; K is O or S; each occurrence of Y is independently -O-, -S-, -NR<2>-, or a bond linking a R<5 >moiety to P; each occurrence of R and R is independently an aliphatic, heteroaliphatic, aryl, or heteroaryl moiety, or H; and each occurrence of R<6 >is independently -PK(YR<5>)(YR<5>), -SO2(YR<5>) or -C(O)(YR<5>); so long as any R or R<5 >moiety linked directly to P is not H; wherein two R<2>, R<5 >and/or R<6 >moieties may be chemically linked to one another to form a ring; each occurrence of G is independently -O-, -S-, -NR<2>- or (M)x; each occurrence of M is independently a substituted or unsubstituted methylene moiety, and any M-M' moiety may be saturated or unsaturated; each occurrence of x is independently an integer from 1-6; and the other variables are as defined herein.
申请公布号 US2004073024(A1) 申请公布日期 2004.04.15
申请号 US20030635054 申请日期 2003.08.06
申请人 METCALF CHESTER A.;ROZAMUS LEONARD W.;WANG YIHAN;BERSTEIN DAVID L. 发明人 METCALF CHESTER A.;ROZAMUS LEONARD W.;WANG YIHAN;BERSTEIN DAVID L.
分类号 A61L27/00;A61F2/84;A61K31/661;A61K31/662;A61K31/664;A61K45/00;A61K45/06;A61P1/04;A61P3/10;A61P9/00;A61P9/10;A61P11/00;A61P17/02;A61P17/04;A61P17/06;A61P19/02;A61P21/04;A61P25/00;A61P25/28;A61P27/02;A61P29/00;A61P31/10;A61P35/00;A61P35/02;A61P37/00;C07D498/18;C07F9/09;C07F9/22;C07F9/32;C07F9/36;C07F9/40;C07F9/44;C07F9/46;C07F9/53;C07F9/6561;(IPC1-7):C07D498/04 主分类号 A61L27/00
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