PROCESS AND INTERMEDIATES FOR THE PREPARATION OF THE THIENOPYRROLE DERIVATIVES

摘要

A process for preparing a compound of formula (I) where R<4> and R<5 >are as defined in the specification; and R<6> is hydrogen or a protecting group, which process comprises cyclisation of a compound of formula (II) where R<4>, R<5>and R<6> are as defined in relation to formula (I) and R<7>is a nitrogen-protecting group, and removing protecting group R<7>-, and thereafter if desired or necessary, removing any protecting group R<6> to obtain the corresponding carboxylic acid. Novel intermediates and the use of the products in the preparation of pharmaceutical compounds is also described and claimed.