发明名称 |
METHOD FOR RATING CANCERATION DEGREE OF MAMMAL-DERIVED SPECIMEN |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for rating the canceration degree of a mammal-derived specimen based on detecting gene abnormality, suitable for evaluating diagnostic or therapeutic methods for discovering cancer at early stages. <P>SOLUTION: This method for rating the canceration degree of the mammal-derived specimen comprises (1) the 1st step of assaying the methylation frequency of Thrombomodulin gene contained in the specimen or an index value correlated with the methylation frequency and (2) the 2nd step of determining the canceration degree based on a difference obtained by comparing the above methylation frequency or index value with the corresponding control. <P>COPYRIGHT: (C)2004,JPO |
申请公布号 |
JP2004113116(A) |
申请公布日期 |
2004.04.15 |
申请号 |
JP20020280687 |
申请日期 |
2002.09.26 |
申请人 |
NATIONAL CANCER CENTER-JAPAN;SUMITOMO CHEM CO LTD |
发明人 |
USHIJIMA TOSHIKAZU;KANEDA ATSUSHI |
分类号 |
G01N33/50;A61K31/7088;A61K45/00;A61K48/00;A61P35/00;C07H21/04;C12N15/09;C12Q1/02;C12Q1/68;G01N33/574 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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