METHOD FOR PRODUCING 2-HYDROXYISOBUTYRIC ACID AND METHACRYLIC ACID FROM ACETONE CYANOHYDRIN
摘要
The present invention relates to a method for producing 2-hydroxyisobutyric acid where acetone cyanohydrin is converted to 2-hydroxyisobutyric acid using an enzyme catalyst having nitrilase activity, or having a combination of nitrile hydratase and amidase activities. The invention also encompasses production of methacrylic acid wherein the 2-hydroxyisobutyric acid produced with the catalyst described is dehydrated to produce methacrylic acid.
申请公布号
WO03066815(A9)
申请公布日期
2004.04.15
申请号
WO2003US03434
申请日期
2003.02.04
申请人
E.I. DU PONT DE NEMOURS AND COMPANY;CHAUHAN, SARITA;DICOSIMO, ROBERT;FALL0N, ROBERT, D.;GAVAGAN, JOHN, E.;MANZER, LEO, E.;PAYNE, MARK, S.
