发明名称 ANTISENSE MODULATION OF TOLL-LIKE RECEPTOR 4 EXPRESSION FIELD OF THE INVENTION
摘要 Antisense compounds, compositions and methods are provided for modulating the expression of Toll-like receptor 4. The compositions comprise antisense compunds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Toll-like receptor 4. Methods of using these compounds for modulation of Toll-like receptor 4 expression and for treatment of diseases associated with expression of Toll-like receptor 4 are provided.
申请公布号 WO03044163(A3) 申请公布日期 2004.04.15
申请号 WO2002US36390 申请日期 2002.11.14
申请人 ISIS PHARMACEUTICALS, INC.;KARRAS, JAMES, G.;KOLLER, ERICH 发明人 KARRAS, JAMES, G.;KOLLER, ERICH
分类号 A61K38/00;C12N15/113 主分类号 A61K38/00
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