ANTISENSE MODULATION OF TOLL-LIKE RECEPTOR 4 EXPRESSION FIELD OF THE INVENTION
摘要
Antisense compounds, compositions and methods are provided for modulating the expression of Toll-like receptor 4. The compositions comprise antisense compunds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Toll-like receptor 4. Methods of using these compounds for modulation of Toll-like receptor 4 expression and for treatment of diseases associated with expression of Toll-like receptor 4 are provided.
申请公布号
WO03044163(A3)
申请公布日期
2004.04.15
申请号
WO2002US36390
申请日期
2002.11.14
申请人
ISIS PHARMACEUTICALS, INC.;KARRAS, JAMES, G.;KOLLER, ERICH