发明名称 |
Method and composition for preventing pain in sickle cell patients |
摘要 |
A method of preventing pain in a sickle cell patient is disclosed. The method includes orally administering to the patient, an amount of an active agent effective on oral administration to inhibit binding of the patient's sickle erythrocytes to P-selectin on the patient's vascular endothelium. The inhibition may be evidenced in a number of ways. The active agent administration inhibits the adhesion of sickle erythrocytes to vascular endothelium in the patient, thereby preventing patient pain associated with vascular occlusion. Also disclosed are compositions useful in practicing the method.
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申请公布号 |
US2004072796(A1) |
申请公布日期 |
2004.04.15 |
申请号 |
US20030418653 |
申请日期 |
2003.04.18 |
申请人 |
EMBURY STEPHEN H.;MATSUI NEIL M. |
发明人 |
EMBURY STEPHEN H.;MATSUI NEIL M. |
分类号 |
A61K31/727;(IPC1-7):A61K31/727 |
主分类号 |
A61K31/727 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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