METHODS AND APPARATUS FOR REDUCING ARTIFACTS IN MASS SPECTROMETERS
摘要
The invention addresses the problem of artifact ghost peaks which can sometimes arise in mass spectrometers that employ a quadrupole rod set for both trapping and mass analyzing the trapped ions. The problem arises as a result of randomly distributed voltage gradients along the length of the rods. Three solutions are presented. The first approach involves improving the conduction characteristics of the rod sets. The second approach involves the application of at least one continuous axial DC field to the trapping quadrupole rod set in order to urge ions towards a pre-determined region of the trap, thereby avoiding voltage gradients. Another approach involves the application of one or more discrete axial fields to create one or more potential barriers along the axial dimension of the trap (in addition to the barriers used to initially trap the ions). These barriers prevent ions of differing voltage gradients from equilibrating with one another.
申请公布号
WO03102517(A3)
申请公布日期
2004.04.15
申请号
WO2003CA00803
申请日期
2003.05.29
申请人
MDS INC., DOING BUSINESS AS MDS SCIEX;LONDRY, FRANK;STOTT, WILLIAM, R.;COLLINGS, BRUCE, A.;HAGER, JAMES
发明人
LONDRY, FRANK;STOTT, WILLIAM, R.;COLLINGS, BRUCE, A.;HAGER, JAMES