| 摘要 |
A bladder carcinoma cell line, which endogenously does not express H19 RNA, shows a marked difference in gene-expression patterns when transfected with H19 sense, as compared with the gene-expression patterns of the same cell line, when transfected with the H19 antisense. In particular, the expression pattern with cells transfected with the H19 sense, showed a marked increase in two unique groups of genes: one group that controls angiogenesis, and another group of genes which protects cells against ischemic stress. |
