APOLIPOPROTEIN L-I FOR THE TREATMENT OR DIAGNOSIS OF PRYPANOSOMALDISEASES

摘要

The present invention is related to a composition comprising apolipoprotein L-I, the use of apolipoprotein L-I or a derivated polypeptide for the diagnostic, the treatment and/or the prevention of diseases induced in mammals by Trypanosoma. Another aspect is related to a transgenic non-human mammal comprising a polynucleotide expressing said apolipoprotein or a derivated polypeptide and which is tolerant or resistant to said Trypanosoma infection.