MULTIMERIC PROTEIN ENGINEERING

摘要

The invention described herein encompasses (1) artificial preproteins and th e polynucleotides encoding them, (2) methods for producing these biomolecules, and (3) methods for their use. The artificial preproproteins of this inventi on comprise a protein assembly capable of producing a multimeric protein from a single protein. Figure 4 illustrates generally the process by which a polynucleotide encoding the artificial preproprotein is introduced into a ce ll and a biomolecule of interest is produced.