发明名称 |
Isoprenoid-dependent ras anchorage (idra) proteins |
摘要 |
Disclosed is the identity of various Ras cell membrane anchor proteins. Also disclosed are methods for identifying other anchor proteins that bind isoforms of Ras, methods of identifying drug candidates that inhibit aberrant Ras activity and methods of determining therapeutic dosages of the drugs. Further disclosed are methods for disrupting aberrant Ras activity in vivo.
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申请公布号 |
US2004072258(A1) |
申请公布日期 |
2004.04.15 |
申请号 |
US20030398519 |
申请日期 |
2003.10.15 |
申请人 |
KLOOG YOEL;HAKLAI RONI;PAZ ARIELLA;EL AD-SFADIA GALIT;BALLAN EYAL |
发明人 |
KLOOG YOEL;HAKLAI RONI;PAZ ARIELLA;EL AD-SFADIA GALIT;BALLAN EYAL |
分类号 |
G01N33/50;A61K9/127;A61K38/00;A61K45/00;A61K48/00;A61P1/16;A61P9/00;A61P9/10;A61P35/00;A61P37/00;C07K14/47;C07K14/82;C12N15/09;G01N33/15;G01N33/53;G01N33/566;(IPC1-7):G01N33/53;G01N33/567;A61K31/441;A61K31/195 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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