摘要 |
PROBLEM TO BE SOLVED: To provide a new VEGF inhibitor and an anticancer agent containing the same as an active ingredient, and a new selective COX-2 inhibitor and an anti-inflammatory agent and anticancer agent containing the same as an active ingredient. SOLUTION: This VEGF inhibitor is expressed by general formula (1) [wherein, R<SP>1</SP>, R<SP>2</SP>are each phenyl, a heterocyclic group, or the phenyl or heterocyclic group of which at least one H is substituted by a group selected from a group consisting of hydroxy, a 1-10C alkyl, a 1-10C alkoxy and R<SP>3</SP>-S- group (wherein, R<SP>3</SP>is a 1-10C alkyl) or a halogen atom, and R<SP>1</SP>, R<SP>2</SP>are each the same or different]. The anticancer agent contains the VEGF inhibitor as the active ingredient. The anti-inflammatory agent and anticancer agent contain the new selective COX-2 inhibitor as the active ingredient. COPYRIGHT: (C)2004,JPO
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