发明名称 |
PROSTATE CANCER BIOMARKERS |
摘要 |
Protein biomarkers that may advantageously be utilized in diagnosing prostate cancer, benign prostate hyperplasia or to make a negative diagnosis are described. Accordingly, in one aspect of the invention, methods for aiding in, or otherwise making, a diagnosis of prostate cancer or benign prostate hyperplasia are provided. In one form of the invention, a method includes detecting various protein biomarkers of defined molecular weight and correlating the detection to a diagnosis of prostate cancer, benign prostate hyperplasia or to a negative diagnosis. In yet another aspect of the invention, kits are provided that may be utilized to detect the biomarkers described herein. In a further of the invention, methods of using a plurality of classifiers to make a probable diagnosis of prostate cancer of benign prostate hyperplasia are provided. In certain forms of the invention, the methods include use of a boosted decision tree analysis. Various computer readable media are also provided. |
申请公布号 |
WO2004030511(A2) |
申请公布日期 |
2004.04.15 |
申请号 |
WO2003US14432 |
申请日期 |
2003.05.09 |
申请人 |
EASTERN VIRGINIA MEDICAL SCHOOL;FRED HUTCHINSON CANCER RESEARCH CENTER;WRIGHT, GEORGE, L., JR.;ADAM, BAO-LING;QU, YINSHENG |
发明人 |
WRIGHT, GEORGE, L., JR.;ADAM, BAO-LING;QU, YINSHENG |
分类号 |
A61B;A61B1/00;C12Q1/68;C12Q1/70;G01N33/574;G01N33/68;G06F19/00;G06F19/18;G06F19/24 |
主分类号 |
A61B |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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