发明名称 |
Combination of antimicrobial agents and bacterial interference to coat medical devices |
摘要 |
This invention relates to a method for coating a medical device comprising the steps of applying to at least a portion of the surface of said medical device, an antimicrobial coating layer and a non-pathogenic bacterial coating layer, wherein the antimicrobial and non-pathogenic bacterial coating layers inhibit the growth of pathogenic bacterial and fungal organisms. The non-pathogenic bacterium used in the bacterial coating layer is resistant to the antimicrobial agent. Furthermore, the non-pathogenic bacterium layer includes at least one of the following: viable whole cells, non-viable whole cells, or cellular structures or extracts. The antimicrobial agent and non-pathogenic bacterium are used to develop a kit comprising these compositions in one container or in separate containers. The kit is used to coat a catheter prior to implantation in a mammal.
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申请公布号 |
US6719991(B2) |
申请公布日期 |
2004.04.13 |
申请号 |
US20010877898 |
申请日期 |
2001.06.08 |
申请人 |
BAYLOR COLLEGE OF MEDICINE |
发明人 |
DAROUICHE RABIH O.;HULL RICHARD |
分类号 |
A61L29/00;A61L29/08;A61L29/16;A61M25/16;(IPC1-7):A61F13/00;A61F2/00;A61M5/00;A61M25/00;A61L27/00 |
主分类号 |
A61L29/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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