摘要 |
A biocompatible substrate for use as a resorbable or non-resorbable implant, graft, prosthesis, etc., has an array of projections or pits of nanometer dimensions on a surface thereof, which resist attachment of cells. Typically the projections or pits are 10-250 nm in size and at spacings of 20-500 nm. The substrate may additionally have areas where cell adhesion is promoted.
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