Wounded epithelium-specific transcript

摘要

The instant invention discloses compositions and methods related to epsin 3, a novel protein closely related to, but distinct from previously described epsins. Epsin 3 mRNA and protein are undetectable in keratinocytes isolated from unwounded skin, but is induced in cells following contact with fibrillar type I collagen. It is envisioned that this protein plays an important role in activated epithelial cells during tissue morphogenesis.