| 发明名称 |
Mutant herpes simplex viruses and uses thereof |
| 摘要 |
The present invention provides a herpes simplex virus strain having a functional ICP27 gene and lacking at lease a functional ICP4 gene and a functional ICP34.5 gene. It also provides the use of a herpes simplex virus strain which lacks at least a functional ICP4 gene and a functional ICP34.5 gene in the treatment of disorders of, or injuries to, the nervous system of a mammal.
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| 申请公布号 |
US6719982(B1) |
申请公布日期 |
2004.04.13 |
| 申请号 |
US20010601102 |
申请日期 |
2001.02.20 |
| 申请人 |
BIOVEX LIMITED |
发明人 |
COFFIN ROBERT S.;LATCHMAN DAVID S.;FINNIE NICHOLAS J. |
| 分类号 |
C12N15/09;A61K35/76;A61K38/00;A61K48/00;A61P25/00;C07K14/035;C12N7/01;C12N7/04;(IPC1-7):A61K39/245;A61K39/12;A61K39/295;C12N15/00 |
主分类号 |
C12N15/09 |
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