FRAGMENTS OF BETA-AMYLOID AS TARGETS FOR VACCINATION AGAINST ALZHEIMER DISEASE

摘要

The invention provides compositions and methods for prevention and treatment of diseases associated with beta-amyloid formation and/or aggregation. Such methods encompass the induction of an immune response against N-terminal truncated and/or post-translationally modified Abeta peptides. These peptides are further used in compositions and methods for the diagnosis of diseases associated with beta-amyloid formation and/or aggregation.