<p>Particles are provided which are suitable for delivery from a particle-mediated delivery device. The particles are obtained by precipitating a nucleic acid on inert metal carrier particles in the presence of a nucleic acid condensing agent and a metal ion chelating agent. Also described are processes for preparing the particles, and therapeutic methods using the particles including methods of nucleic acid immunisation and gene therapy.</p>
申请公布号
WO2004028560(A1)
申请公布日期
2004.04.08
申请号
WO2003GB04202
申请日期
2003.09.29
申请人
POWDERJECT RESEARCH LIMITED;LIVELY, CHRIS, ROBERT;DELONG, ROBERT