| 发明名称 |
Compounds useful for the inhibition of ALDH |
| 摘要 |
The present invention provides novel antidipsotropic compounds. The invention further provides methods of inhibiting ALDH-2 using the compounds described herein. Methods for modulating alcohol consumption, alcohol dependence and/or alcohol abuse by administering the compounds of the invention to an individual are also provided. The present invention further provides a rationale for designing additional novel antidipsotropic compounds.
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| 申请公布号 |
US2004068003(A1) |
申请公布日期 |
2004.04.08 |
| 申请号 |
US20030609120 |
申请日期 |
2003.06.27 |
| 申请人 |
THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC, |
发明人 |
KEUNG WING MING;VALLEE BERT L.;GAO GUANGYAO |
| 分类号 |
A61K31/352;A61K31/353;C07D311/34;C07D405/12;C07D405/14;C07D407/12;C07D417/12;C07H17/07;C12Q1/32;(IPC1-7):A61K31/353 |
主分类号 |
A61K31/352 |
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