发明名称 TRPS AS MODIFIERS OF THE p53 PATHWAY AND METHODS OF USE
摘要 Human TRP genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising for agents that modulate the activity of TRP are provided.
申请公布号 WO03014300(A3) 申请公布日期 2004.04.08
申请号 WO2002US24624 申请日期 2002.08.02
申请人 EXELIXIS, INC.;FRIEDMAN, LORI;PLOWMAN, GREGORY, D.;FRANCIS-LANG, HELEN;LI, DANXI;FUNKE, ROEL, P. 发明人 FRIEDMAN, LORI;PLOWMAN, GREGORY, D.;FRANCIS-LANG, HELEN;LI, DANXI;FUNKE, ROEL, P.
分类号 C12N15/09;A61K31/7052;A61K31/7088;A61K31/7105;A61K38/00;A61K39/395;A61K45/00;A61P9/00;A61P35/00;A61P43/00;C12Q1/02;C12Q1/48;C12Q1/68;G01N33/15;G01N33/50;G01N33/574;G01N33/68 主分类号 C12N15/09
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