发明名称 NOVEL PYRIDAZINE DERIVATIVES, USE OF THE SAME AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND METHOD FOR PRODUCING THE SAME
摘要 The invention relates to the products of formula (I) wherein R1 represents a hydrogen atom or an optionally substituted alkyl, COR, COOR, aryl, or aralkyl radical; R2 represents a radical of formula (II) wherein n is equal to 0, 1, 2 or 3, and X can be a saturated or unsaturated, monocyclic or bicyclic heterocycle radical, an aryl radical, a NR4R5 radical, or a COR radical; and R3 is a radical of formula -Y-(CH2)m-C(CN)R6R7 wherein Y is an oxygen atom or a -N(R8)- radical, and m is equal to 0, 1, 2 or 3. The inventive products are used for the prevention or treatment of diseases with which metabolic enzymes selected from proteases and kinases are associated.
申请公布号 WO03068140(A3) 申请公布日期 2004.04.08
申请号 WO2003FR00381 申请日期 2003.02.07
申请人 AVENTIS PHARMA S.A.;BHATNAGAR, NEERJA;BENARD, DIDIER;BROTO, PIERRE;GOURVEST, JEAN-FRANCOIS;MAUGER, JACQUES 发明人 BHATNAGAR, NEERJA;BENARD, DIDIER;BROTO, PIERRE;GOURVEST, JEAN-FRANCOIS;MAUGER, JACQUES
分类号 A61K31/50;A61K31/5377;A61P1/02;A61P3/14;A61P5/24;A61P5/38;A61P9/00;A61P9/10;A61P9/12;A61P19/00;A61P19/02;A61P19/08;A61P19/10;A61P25/00;A61P25/28;A61P29/00;A61P31/00;A61P35/00;A61P37/08;A61P43/00;C07D237/04;C07D413/02 主分类号 A61K31/50
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