发明名称 |
NOVEL PYRIDAZINE DERIVATIVES, USE OF THE SAME AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND METHOD FOR PRODUCING THE SAME |
摘要 |
The invention relates to the products of formula (I) wherein R1 represents a hydrogen atom or an optionally substituted alkyl, COR, COOR, aryl, or aralkyl radical; R2 represents a radical of formula (II) wherein n is equal to 0, 1, 2 or 3, and X can be a saturated or unsaturated, monocyclic or bicyclic heterocycle radical, an aryl radical, a NR4R5 radical, or a COR radical; and R3 is a radical of formula -Y-(CH2)m-C(CN)R6R7 wherein Y is an oxygen atom or a -N(R8)- radical, and m is equal to 0, 1, 2 or 3. The inventive products are used for the prevention or treatment of diseases with which metabolic enzymes selected from proteases and kinases are associated. |
申请公布号 |
WO03068140(A3) |
申请公布日期 |
2004.04.08 |
申请号 |
WO2003FR00381 |
申请日期 |
2003.02.07 |
申请人 |
AVENTIS PHARMA S.A.;BHATNAGAR, NEERJA;BENARD, DIDIER;BROTO, PIERRE;GOURVEST, JEAN-FRANCOIS;MAUGER, JACQUES |
发明人 |
BHATNAGAR, NEERJA;BENARD, DIDIER;BROTO, PIERRE;GOURVEST, JEAN-FRANCOIS;MAUGER, JACQUES |
分类号 |
A61K31/50;A61K31/5377;A61P1/02;A61P3/14;A61P5/24;A61P5/38;A61P9/00;A61P9/10;A61P9/12;A61P19/00;A61P19/02;A61P19/08;A61P19/10;A61P25/00;A61P25/28;A61P29/00;A61P31/00;A61P35/00;A61P37/08;A61P43/00;C07D237/04;C07D413/02 |
主分类号 |
A61K31/50 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|