STILBENE DERIVATIVE HAVING CYTOCHROME P450 1B1 INHIBITORY ACTIVITY, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, METHOD FOR PREPARING THE SAME, AND COMPOSITION INCLUDING THE SAME

摘要

A stilbene derivative having cytochrome P450 1B1 inhibitory activity, pharmaceutically acceptable salt thereof, method for preparing the same, and composition including the same are disclosed. The stilbene derivative is a strong and selective inhibitor of cytochrome P450 1B1, thereby to decrease or prevent chemical carcinogenesis in mammals, in particular the development of a breast cancer, and can be used as a pharmaceutical tool to elucidate the function of cytochrome P450.