| 摘要 |
The present invention relates to a matrix type patch for transdermal administration of vitamin D analog and the use thereof.The preparation of a matrix type patch for transdermal administration is characterized by including adhesive layer, which contains (1) 0.0001 to 10 % by weight of vitamin D analog; and (2) 90 to 99.9999 % by weight of nonpolar adhesive polymer and it maintains effective vitamin D analog concentration of the blood for long period and constant permeation of the drug with reduced skin irritation.The present invention can be used to treat diseases which need vitamin D analog, such as osteoporosis, renal failure and thyroid dysfunction. |
