| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a recombinant virus providing increased safety compared with an already-known recombinant virus, and a method for producing such recombinant viruses. <P>SOLUTION: A recombinant avipox virus includes a recombinant poxvirus, especially a fowlpox virus attenuated by serial passage in embryonated hen eggs, subsequent serial passage in chick embryo fibroblasts, successive plaque purification of a master seed of the virus, and amplification in primary CEF cells. <P>COPYRIGHT: (C)2004,JPO |
