发明名称 |
Pharmaceutical formulation |
摘要 |
The present invention relates to a pharmaceutical formulation comprising bicalutamide and an enteric polymer having a pKa from 3 to 6. The invention also relates to a daily pharmaceutical dose of bicalutamide provided by such a formulation. In addition, the invention relates to the use of such an enteric polymer in solid dispersion with bicalutamide for increasing the bioavailability of the bicalutamide; for reducing inter-patient variability in plasma concentrations of bicalutamide; or for treating and/or reducing the risk of prostate cancer in a patient.
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申请公布号 |
US2004067257(A1) |
申请公布日期 |
2004.04.08 |
申请号 |
US20030468276 |
申请日期 |
2003.08.18 |
申请人 |
BATEMAN NICOLA;CAHILL JLULIE |
发明人 |
BATEMAN NICOLA;CAHILL JLULIE |
分类号 |
A61K9/14;A61K9/00;A61K9/16;A61K9/32;A61K9/36;A61K31/167;A61K31/277;A61K47/32;A61K47/38;A61P5/28;A61P13/08;A61P35/00;(IPC1-7):A61K31/277;A61K9/24 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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