发明名称 |
Synthesis and characterization of novel systems for guidance and vectorization of molecules of therapeutic interest towards target cells |
摘要 |
<p>A method for preparing a grafted homodetic cyclopeptide forming a framework that defines a grafted upper face and grafted lower face, including synthesizing a linear peptide from modified or unmodified amino acids, some of which carry orthogonal protective groups; intramolecular cyclizing the resulting protected linear peptide; substituting some or all of orthogonal protective groups with a protected precursor; and grafting at least one molecule of interest onto one and/or the other face of the framework via an oxime bond.</p> |
申请公布号 |
AU2003299038(A8) |
申请公布日期 |
2004.04.08 |
申请号 |
AU20030299038 |
申请日期 |
2003.09.19 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS;UNIVERSITE JOSEPH FOURIER;INSERM |
发明人 |
PASCAL DUMY;MARIE-CHRISTINE FAVROT;DIDIER BOTURYN;JEAN-LUC COLL |
分类号 |
A61K38/00;A61P35/00;C07K7/64;C07K9/00;(IPC1-7):C07K1/08;C07K19/00;A61K38/12 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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