| 发明名称 |
PROCESS FOR THE PREPARATION 3-ARYL-2-HYDROXYPROPIONIC ACID DERIVATIVE |
| 摘要 |
<p>A process for the preparation of a compound of formula I in which R represents H or an acid protecting group which comprises reacting a compound of formula II in which R is as previously defined with a compound of formula III wherein X is a suitable leaving group in the presence of a base and a phase transfer catalyst at a temperature in the range 50° C. to 150° C.</p> |
| 申请公布号 |
EP1404651(A1) |
申请公布日期 |
2004.04.07 |
| 申请号 |
EP20020736372 |
申请日期 |
2002.05.30 |
| 申请人 |
ASTRAZENECA AB |
发明人 |
EHRL, ROBERT;IOANNIDIS, PANAGIOTIS;MACKINTOSH, WILLIAM |
| 分类号 |
A61K;C07B61/00;C07C;C07C303/30;C07C309/66;(IPC1-7):C07C309/66;A61K31/19 |
主分类号 |
A61K |
| 代理机构 |
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代理人 |
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| 主权项 |
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