摘要 |
FIELD: organic chemistry, heterocyclic compounds, purines, medicine. ^ SUBSTANCE: invention relates to a method for treatment of arrhythmia in mammal. Method involves administration of agonist of adenosine A1-receptors in the therapeutically effective minimal dose of the formula: ^ wherein R1 represents optionally substituted heterocyclic group. The indicated dose of agonist is in the range from 0.0003 to 0.009 mg/kg. Method shows the enhanced effectiveness and doesn't result to undesirable adverse effects. ^ EFFECT: improved treatment method, valuable medicinal properties of substances. ^ 11 cl, 1 dwg, 2 ex |